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Vif determines the requirement for CBF-β in APOBEC3 degradation

APOBEC3 (apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3) proteins are cellular DNA deaminases that restrict a broad spectrum of lentiviruses. This process is counteracted by Vif (viral infectivity factor) of lentiviruses, which binds APOBEC3s and promotes their degradation. CBF-β...

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Bibliographische Detailangaben
Veröffentlicht in:J Gen Virol
Hauptverfasser: Yoshikawa, Rokusuke, Takeuchi, Junko S., Yamada, Eri, Nakano, Yusuke, Ren, Fengrong, Tanaka, Hiroshi, Münk, Carsten, Harris, Reuben S., Miyazawa, Takayuki, Koyanagi, Yoshio, Sato, Kei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for General Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361795/
https://ncbi.nlm.nih.gov/pubmed/25516542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000027
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