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Vif determines the requirement for CBF-β in APOBEC3 degradation
APOBEC3 (apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3) proteins are cellular DNA deaminases that restrict a broad spectrum of lentiviruses. This process is counteracted by Vif (viral infectivity factor) of lentiviruses, which binds APOBEC3s and promotes their degradation. CBF-β...
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| Veröffentlicht in: | J Gen Virol |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for General Microbiology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361795/ https://ncbi.nlm.nih.gov/pubmed/25516542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000027 |
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