A conflict of interest: the evolutionary arms race between mammalian APOBEC3 and lentiviral Vif

Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3) proteins are mammalian-specific cellular deaminases and have a robust ability to restrain lentivirus replication. To antagonize APOBEC3-mediated antiviral action, lentiviruses have acquired viral infectivity factor (Vif) as...

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Publicado en:Retrovirology
Autores principales: Nakano, Yusuke, Aso, Hirofumi, Soper, Andrew, Yamada, Eri, Moriwaki, Miyu, Juarez-Fernandez, Guillermo, Koyanagi, Yoshio, Sato, Kei
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422959/
https://ncbi.nlm.nih.gov/pubmed/28482907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0355-4
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