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Simian Immunodeficiency Virus Vif and Human APOBEC3B Interactions Resemble Those between HIV-1 Vif and Human APOBEC3G

Several members of the APOBEC3 DNA cytosine deaminase family can potently inhibit Vif-deficient human immunodeficiency virus type 1 (HIV-1) by catalyzing cytosine deamination in viral cDNA and impeding reverse transcription. HIV-1 counteracts restriction with the virally encoded Vif protein, which t...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Wang, Jiayi, Shaban, Nadine M., Land, Allison M., Brown, William L., Harris, Reuben S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974497/
https://ncbi.nlm.nih.gov/pubmed/29618650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00447-18
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