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Catalytic Activity of APOBEC3F Is Required for Efficient Restriction of Vif-deficient Human Immunodeficiency Virus

APOBEC3 proteins are DNA cytosine deaminases that restrict the replication of human immunodeficiency virus deficient in the counterdefense protein Vif. Here, we address the capacity of APOBEC3F to restrict via deaminase-dependent and -independent mechanisms by monitoring spreading infections in dive...

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Detalhes bibliográficos
Main Authors: Albin, John S., Brown, William L., Harris, Reuben S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932626/
https://ncbi.nlm.nih.gov/pubmed/24503066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.11.041
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