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Optimal Translation Initiation Enables Vif-Deficient Human Immunodeficiency Virus Type 1 To Escape Restriction by APOBEC3G

APOBEC3G restricts Vif-deficient human immunodeficiency virus type 1 (HIV-1) by deaminating viral cDNA cytosines to uracils. This promutagenic activity is counteracted by HIV-1 Vif, which is a natural APOBEC3G antagonist. However, we previously reported that Vif-deficient HIV-1 could evolve resistan...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Haché, Guylaine, Abbink, Truus E. M., Berkhout, Ben, Harris, Reuben S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681989/
https://ncbi.nlm.nih.gov/pubmed/19297501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00045-09
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