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RNA Structure Modulates Splicing Efficiency at the Human Immunodeficiency Virus Type 1 Major Splice Donor

The untranslated leader of the human immunodeficiency virus type 1 (HIV-1) RNA genome encodes essential sequence and structural motifs that control various replication steps. The 5′ splice site or splice donor (SD) is embedded in a semistable hairpin, but the function of this structure is unknown. W...

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Sonraí Bibleagrafaíochta
Main Authors: Abbink, Truus E. M., Berkhout, Ben
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258995/
https://ncbi.nlm.nih.gov/pubmed/18160437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01479-07
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