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The Binding Interface Between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches
APOBEC3 family DNA cytosine deaminases provide overlapping defenses against pathogen infections. However, most viruses have elaborate evasion mechanisms such as the HIV-1 Vif protein, which subverts cellular CBF-β and a polyubiquitin ligase complex to neutralize these enzymes. Despite advances in AP...
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| Gepubliceerd in: | Cell Rep |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684092/ https://ncbi.nlm.nih.gov/pubmed/26628363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.067 |
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