The Binding Interface Between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches

APOBEC3 family DNA cytosine deaminases provide overlapping defenses against pathogen infections. However, most viruses have elaborate evasion mechanisms such as the HIV-1 Vif protein, which subverts cellular CBF-β and a polyubiquitin ligase complex to neutralize these enzymes. Despite advances in AP...

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發表在:Cell Rep
Main Authors: Richards, Christopher, Albin, John S., Demir, Özlem, Shaban, Nadine M., Luengas, Elizabeth M., Land, Allison M., Anderson, Brett D., Holten, John R., Anderson, John S., Harki, Daniel A., Amaro, Rommie E., Harris, Reuben S.
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684092/
https://ncbi.nlm.nih.gov/pubmed/26628363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.067
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