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Reassessing APOBEC3G inhibition by HIV-1 Vif-derived peptides
The human APOBEC3G (A3G) enzyme restricts HIV-1 in the absence of the viral accessory protein viral infectivity factor (Vif) by deaminating viral cDNA cytosines to uracils. These uracil lesions base-pair with adenines during the completion of reverse transcription and result in A3G signature G-to-A...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5186364/ https://ncbi.nlm.nih.gov/pubmed/27887868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.11.012 |
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