Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces

APOBEC3G is a DNA cytidine deaminase that has anti-viral activity against HIV-1 and other pathogenic viruses. In this study the crystal structure of the catalytically active C-terminal domain was determined to 2.25 Å. This structure corroborates features previously observed in NMR studies, a bulge i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shandilya, Shivender M. D., Nalam, Madhavi N. L., Nalivaika, Ellen A., Gross, Phillip J., Valesano, John C., Shindo, Keisuke, Li, Ming, Munson, Mary, Harjes, Elena, Kouno, Takahide, Matsuo, Hiroshi, Harris, Reuben S., Somasundaran, Mohan, Schiffer, Celia A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913127/
https://ncbi.nlm.nih.gov/pubmed/20152150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.10.016
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg