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1-Deoxygalactonojirimycin-lysine hybrids as potent D-galactosidase inhibitors

Cyclization by double reductive amination of L-arabino-hexos-5-ulose with suitably protected D- as well as L-lysine derivatives provided 1-deoxygalactonojirimycin lysine hybrids without any observable epimer formation at C-5. Modifications on the lysine moiety by acylation gave access to lipophilic...

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Bibliografski detalji
Glavni autori: Steiner, Andreas J., Schitter, Georg, Stütz, Arnold E., Wrodnigg, Tanja M., Tarling, Chris A., Withers, Stephen G., Fantur, Katrin, Mahuran, Don, Paschke, Eduard, Tropak, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910748/
https://ncbi.nlm.nih.gov/pubmed/18996021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.10.054
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