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1-Deoxygalactonojirimycin-lysine hybrids as potent D-galactosidase inhibitors
Cyclization by double reductive amination of L-arabino-hexos-5-ulose with suitably protected D- as well as L-lysine derivatives provided 1-deoxygalactonojirimycin lysine hybrids without any observable epimer formation at C-5. Modifications on the lysine moiety by acylation gave access to lipophilic...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910748/ https://ncbi.nlm.nih.gov/pubmed/18996021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.10.054 |
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