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2-Acetamino-1,2-dideoxynojirimycin—lysine hybrids as hexosaminidase inhibitors
Cyclisation by double reductive amination of 2-acetamino-2-deoxy-D-xylo-hexos-5-ulose with N-2 protected L-lysine derivatives provided 2-acetamino-1,2-dideoxynojirimycin derivatives without any observable epimer formation at C-5. Modifications on the lysine moiety gave access to lipophilic derivativ...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276585/ https://ncbi.nlm.nih.gov/pubmed/22328804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetasy.2009.02.015 |
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