Fluorous Iminoalditols: A New Family of Glycosidase Inhibitors and Pharmacological Chaperones

A collection of new reversible glycosidase inhibitors of the iminoalditol type featuring N-substituents containing perfluorinated regions has been prepared for evaluation of physicochemical, biochemical and diagnostic properties. The vast variety of feasible oligofluoro moieties allows for modular a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schitter, Georg, Steiner, Andreas J., Pototschnig, Gerit, Scheucher, Elisabeth, Thonhofer, Martin, Tarling, Chris A., Withers, Stephen G., Fantur, Katrin, Paschke, Eduard, Mahuran, Don J., Rigat, Brigitte A., Tropak, Michael B., Illaszewicz, Carina, Saf, Robert, Stütz, Arnold E., Wrodnigg, Tanja M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198847/
https://ncbi.nlm.nih.gov/pubmed/20715263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201000192
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