1-Deoxy-d-galactonojirimycins with dansyl capped N-substituents as β-galactosidase inhibitors and potential probes for G(M1) gangliosidosis affected cell lines

Two simple and reliably accessible intermediates, N-carboxypentyl- and N-aminohexyl-1-deoxy-d-galactonojirimycin were employed for the synthesis of a set of terminally N-dansyl substituted derivatives. Reaction of the terminal carboxylic acid of N-carboxypentyl-1-deoxy-d-galactonojirimycin with N-da...

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Detalhes bibliográficos
Main Authors: Fröhlich, Richard F.G., Furneaux, Richard H., Mahuran, Don J., Saf, Robert, Stütz, Arnold E., Tropak, Michael B., Wicki, Jacqueline, Withers, Stephen G., Wrodnigg, Tanja M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158671/
https://ncbi.nlm.nih.gov/pubmed/21645885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2011.05.010
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