PYRIMETHAMINE AS A POTENTIAL PHARMACOLOGICAL CHAPERONE FOR LATE-ONSET FORMS OF GM2 GANGLIOSIDOSIS

Lignende værker

• The Natural History of Juvenile or Subacute GM2 Gangliosidosis: 21 New Cases and Literature Review of 134 Previously Reported
  af: Maegawa, Gustavo H. B., et al.
  Udgivet: (2006)
• An open-label Phase I/II clinical trial of pyrimethamine for the treatment of patients affected with chronic GM2 gangliosidosis (Tay–Sachs or Sandhoff variants)
  af: Clarke, Joe T.R., et al.
  Udgivet: (2010)
• Crystal Structure of β-Hexosaminidase B in Complex with Pyrimethamine, a Potential Pharmacological Chaperone()
  af: Bateman, Katherine S., et al.
  Udgivet: (2011)
• Evaluation of N-nonyl-deoxygalactonojirimycin as a pharmacological chaperone for human GM1 gangliosidosis leads to identification of a feline model suitable for testing enzyme enhancement therapy
  af: Rigat, Brigitte A., et al.
  Udgivet: (2012)
• Lending a helping hand, screening chemical libraries for compounds that enhance β-hexosaminidase A activity in GM2 gangliosidosis cells
  af: Tropak, Michael B., et al.
  Udgivet: (2007)