लोड हो रहा है...

PYRIMETHAMINE AS A POTENTIAL PHARMACOLOGICAL CHAPERONE FOR LATE-ONSET FORMS OF GM2 GANGLIOSIDOSIS

Late-onset GM2-gangliosidosis (GM2) is composed of two related, autosomal recessive, neurodegenerative diseases, both resulting from deficiency of lysosomal, heterodimeric β-hexosaminidase A (Hex A, αβ). Pharmacological chaperones (PC) are small molecules that can stabilize the conformation of a mut...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Maegawa, Gustavo H. B., Tropak, Michael, Butner, Justin, Stockley, Tracy, Kok, Fernando, Clarke, Joe T. R., Mahuran, Don J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2007
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851921/
https://ncbi.nlm.nih.gov/pubmed/17237499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609304200
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!