1-Deoxynojirimycins with dansyl capped N-substituents as probes for Morbus Gaucher affected cell lines

Cyclization by double reductive amination of D-xylo-hexos-5-ulose with methyl 6-aminohexanoate gave (methoxycarbonyl)pentyl-1-deoxynojirimycin. Reaction of the terminal carboxylic acid with N-dansyl- 1,6-diaminohexane provided the corresponding chain-extended fluorescent derivative. By reaction with...

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Detalhes bibliográficos
Main Authors: Fröhlich, Richard F. G., Furneaux, Richard H., Mahuran, Don J., Rigat, Brigitte A., Stütz, Arnold E., Tropak, Michael B., Wicki, Jacqueline, Withers, Stephen G., Wrodnigg, Tanja M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201982/
https://ncbi.nlm.nih.gov/pubmed/20471633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2010.04.015
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