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Role of Zinc in Human Islet Amyloid Polypeptide Aggregation
Human Islet Amyloid Polypeptide (hIAPP) is a highly amyloidogenic protein found in islet cells of patients with type II diabetes. Because hIAPP is highly toxic to beta-cells under certain conditions, it has been proposed that hIAPP is linked to the loss of beta-cells and insulin secretion in type II...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904811/ https://ncbi.nlm.nih.gov/pubmed/20536124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1007867 |
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