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Three-Dimensional Structure and Orientation of Rat Islet Amyloid Polypeptide Protein in a Membrane Environment by Solution NMR Spectroscopy

Islet amyloid polypeptide (IAPP or amylin) is a 37-residue peptide hormone associated with glucose metabolism that is cosecreted with insulin by β-cells in the pancreas. Since human IAPP is a highly amyloidogenic peptide, it has been suggested that the formation of IAPP amyloid fibers is responsible...

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Hlavní autoři: Nanga, Ravi Prakash Reddy, Brender, Jeffrey R., Xu, Jiadi, Hartman, Kevin, Subramanian, Vivekanandan, Ramamoorthy, Ayyalusamy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163022/
https://ncbi.nlm.nih.gov/pubmed/19456151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9010095
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