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Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120

We evaluated the potential of a quartz crystal microbalance with dissipation monitoring (QCM-D) to provide a sensitive, label-free method for detecting the conformational rearrangement of glycoprotein gp120 upon binding to different ligands. This glycoprotein is normally found on the envelope of the...

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Detalhes bibliográficos
Main Authors: Lee, Hyun-Su, Contarino, Mark, Umashankara, M., Schön, Arne, Freire, Ernesto, Smith, Amos B., Chaiken, Irwin M., Penn, Lynn S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903444/
https://ncbi.nlm.nih.gov/pubmed/20016882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-009-3313-8
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