Inhibition of FOXO3 Tumor Suppressor Function by βTrCP1 through Ubiquitin-Mediated Degradation in a Tumor Mouse Model

BACKGROUND: The ubiquitin-proteasome system is the primary proteolysis machine for controlling protein stability of the majority of regulatory proteins including those that are critical for cancer development. The forkhead box transcription factor FOXO3 plays a key role in regulating tumor suppressi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Tsai, Wen-Bin, Chung, Young Min, Zou, Yiyu, Park, See-Hyoung, Xu, Zhaohui, Nakayama, Keiko, Lin, Sue-Hwa, Hu, Mickey C-T.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896402/
https://ncbi.nlm.nih.gov/pubmed/20625400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011171
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker