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βTrCP regulates BMI1 protein turnover via ubiquitination and degradation
The polycomb group protein BMI1 has been linked to proliferation, senescence, cancer progression and stem cell phenotype. At present, very little is known about its regulation. Here, we report that BMI1 contains a functional recognition motif for the F box protein βTrCP, which regulates ubiquitinati...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117138/ https://ncbi.nlm.nih.gov/pubmed/21430439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.8.15372 |
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