Φορτώνει......
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs
The mammalian target of rapamycin complex 1 (mTORC1) integrates mitogen and nutrient signals to control cell proliferation and cell size. Hence, mTORC1 is implicated in a large number of human diseases--including diabetes, obesity, heart disease, and cancer--that are characterized by aberrant cell g...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893390/ https://ncbi.nlm.nih.gov/pubmed/20508131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1187532 |
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