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Epigenetic Activation of a Subset of mRNAs by eIF4E Explains Its Effects on Cell Proliferation
BACKGROUND: Translation deregulation is an important mechanism that causes aberrant cell growth, proliferation and survival. eIF4E, the mRNA 5′ cap-binding protein, plays a major role in translational control. To understand how eIF4E affects cell proliferation and survival, we studied mRNA targets t...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1797416/ https://ncbi.nlm.nih.gov/pubmed/17311107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000242 |
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