Llwytho...

Structure of the human mTOR Complex I and its implications for rapamycin inhibition

The mammalian Target of Rapamycin Complex 1 (mTORC1) regulates cell growth in response to the nutrient and energy status of the cell, and its deregulation is common in human cancers. Little is known about the overall architecture and subunit organization of this essential signaling complex. We have...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yip, Calvin K., Murata, Kazuyoshi, Walz, Thomas, Sabatini, David M., Kang, Seong A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887672/
https://ncbi.nlm.nih.gov/pubmed/20542007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.05.017
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