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Rapamycin and mTOR: a serendipitous discovery and implications for breast cancer
Rapamycin was discovered more than thirty years ago from a soil sample from the island of Rapa Nui. It was isolated from Streptomyces hygroscopicus and initial characterization focused on its antifungal activities. Subsequent characterization showed that it has immunosuppressive properties and has b...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Springer
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561035/ https://ncbi.nlm.nih.gov/pubmed/23369283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2001-1326-1-29 |
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