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Estimating genome-wide IBD sharing from SNP data via an efficient hidden Markov model of LD with application to gene mapping
Motivation: Association analysis is the method of choice for studying complex multifactorial diseases. The premise of this method is that affected persons contain some common genomic regions with similar SNP alleles and such areas will be found in this analysis. An important disadvantage of GWA stud...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881389/ https://ncbi.nlm.nih.gov/pubmed/20529903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq204 |
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