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Recognition of beta-structural motifs using hidden Markov models trained with simulated evolution

Motivation: One of the most successful methods to date for recognizing protein sequences that are evolutionarily related, has been profile hidden Markov models. However, these models do not capture pairwise statistical preferences of residues that are hydrogen bonded in β-sheets. We thus explore met...

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Bibliografische gegevens
Hoofdauteurs: Kumar, Anoop, Cowen, Lenore
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881384/
https://ncbi.nlm.nih.gov/pubmed/20529918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq199
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