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Sparse multitask regression for identifying common mechanism of response to therapeutic targets

Motivation: Molecular association of phenotypic responses is an important step in hypothesis generation and for initiating design of new experiments. Current practices for associating gene expression data with multidimensional phenotypic data are typically (i) performed one-to-one, i.e. each gene is...

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Detalhes bibliográficos
Main Authors: Zhang, Kai, Gray, Joe W., Parvin, Bahram
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881366/
https://ncbi.nlm.nih.gov/pubmed/20529943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq181
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