A dynamic Bayesian network for identifying protein-binding footprints from single molecule-based sequencing data

Motivation: A global map of transcription factor binding sites (TFBSs) is critical to understanding gene regulation and genome function. DNaseI digestion of chromatin coupled with massively parallel sequencing (digital genomic footprinting) enables the identification of protein-binding footprints wi...

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Hlavní autoři: Chen, Xiaoyu, Hoffman, Michael M., Bilmes, Jeff A., Hesselberth, Jay R., Noble, William S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Ismb 2010 Conference Proceedings July 11 to July 13, 2010, Boston, Ma, Usa
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881360/
https://ncbi.nlm.nih.gov/pubmed/20529925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq175
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