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A dynamic Bayesian network for identifying protein-binding footprints from single molecule-based sequencing data
Motivation: A global map of transcription factor binding sites (TFBSs) is critical to understanding gene regulation and genome function. DNaseI digestion of chromatin coupled with massively parallel sequencing (digital genomic footprinting) enables the identification of protein-binding footprints wi...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881360/ https://ncbi.nlm.nih.gov/pubmed/20529925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq175 |
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