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A dynamic Bayesian network for identifying protein-binding footprints from single molecule-based sequencing data

Motivation: A global map of transcription factor binding sites (TFBSs) is critical to understanding gene regulation and genome function. DNaseI digestion of chromatin coupled with massively parallel sequencing (digital genomic footprinting) enables the identification of protein-binding footprints wi...

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Detalhes bibliográficos
Main Authors: Chen, Xiaoyu, Hoffman, Michael M., Bilmes, Jeff A., Hesselberth, Jay R., Noble, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881360/
https://ncbi.nlm.nih.gov/pubmed/20529925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq175
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