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Estimating genome-wide IBD sharing from SNP data via an efficient hidden Markov model of LD with application to gene mapping

Motivation: Association analysis is the method of choice for studying complex multifactorial diseases. The premise of this method is that affected persons contain some common genomic regions with similar SNP alleles and such areas will be found in this analysis. An important disadvantage of GWA stud...

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Detalhes bibliográficos
Main Authors: Bercovici, Sivan, Meek, Christopher, Wexler, Ydo, Geiger, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881389/
https://ncbi.nlm.nih.gov/pubmed/20529903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq204
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