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Estimating genome-wide IBD sharing from SNP data via an efficient hidden Markov model of LD with application to gene mapping

Motivation: Association analysis is the method of choice for studying complex multifactorial diseases. The premise of this method is that affected persons contain some common genomic regions with similar SNP alleles and such areas will be found in this analysis. An important disadvantage of GWA stud...

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Bibliografische gegevens
Hoofdauteurs: Bercovici, Sivan, Meek, Christopher, Wexler, Ydo, Geiger, Dan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881389/
https://ncbi.nlm.nih.gov/pubmed/20529903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq204
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