Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM

Motivation: High-throughput data is providing a comprehensive view of the molecular changes in cancer tissues. New technologies allow for the simultaneous genome-wide assay of the state of genome copy number variation, gene expression, DNA methylation and epigenetics of tumor samples and cancer cell...

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Detalhes bibliográficos
Main Authors: Vaske, Charles J., Benz, Stephen C., Sanborn, J. Zachary, Earl, Dent, Szeto, Christopher, Zhu, Jingchun, Haussler, David, Stuart, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Ismb 2010 Conference Proceedings July 11 to July 13, 2010, Boston, Ma, Usa
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881367/
https://ncbi.nlm.nih.gov/pubmed/20529912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq182
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