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Recognition of beta-structural motifs using hidden Markov models trained with simulated evolution

Motivation: One of the most successful methods to date for recognizing protein sequences that are evolutionarily related, has been profile hidden Markov models. However, these models do not capture pairwise statistical preferences of residues that are hydrogen bonded in β-sheets. We thus explore met...

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Bibliografski detalji
Glavni autori: Kumar, Anoop, Cowen, Lenore
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881384/
https://ncbi.nlm.nih.gov/pubmed/20529918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq199
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