Loss of Blm enhances basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Ptch1(+/−) mice

Basal cell carcinomas (BCCs) have relative genomic stability and relatively benign clinical behavior but whether these two are related causally is unknown. To investigate the effects of introducing genomic instability into murine BCCs, we have compared ionizing radiation-induced tumorigenesis in Ptc...

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Autores principales: Davari, Parastoo, Hebert, Jennifer L., Albertson, Donna G., Huey, Bing, Roy, Ritu, Mancianti, Maria L., Horvai, Andrew E., McDaniel, Lisa D., Schultz, Roger A., Epstein, Ervin H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Cancer Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878356/
https://ncbi.nlm.nih.gov/pubmed/19995795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp309
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