Congenital embryonal rhabdomyosarcoma caused by heterozygous concomitant PTCH1 and PTCH2 germline mutations

The sonic hedgehog (SHH) signaling pathway has been shown to play important roles in embryogenesis, cell proliferation as well as in cell differentiation. It is aberrantly activated in various common cancers in adults, but also in pediatric neoplasms, such as rhabdomyosarcoma (RMS) and atypical tera...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:Eur J Hum Genet
Główni autorzy: Taeubner, Julia, Brozou, Triantafyllia, Qin, Nan, Bartl, Jasmin, Ginzel, Sebastian, Schaper, Joerg, Felsberg, Joerg, Fulda, Simone, Vokuhl, Christian, Borkhardt, Arndt, Kuhlen, Michaela
Format: Artigo
Język:Inglês
Wydane: Nature Publishing Group UK 2017
Hasła przedmiotowe:
Brief Communication
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839031/
https://ncbi.nlm.nih.gov/pubmed/29230040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-017-0048-4
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