Congenital embryonal rhabdomyosarcoma caused by heterozygous concomitant PTCH1 and PTCH2 germline mutations

The sonic hedgehog (SHH) signaling pathway has been shown to play important roles in embryogenesis, cell proliferation as well as in cell differentiation. It is aberrantly activated in various common cancers in adults, but also in pediatric neoplasms, such as rhabdomyosarcoma (RMS) and atypical tera...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Taeubner, Julia, Brozou, Triantafyllia, Qin, Nan, Bartl, Jasmin, Ginzel, Sebastian, Schaper, Joerg, Felsberg, Joerg, Fulda, Simone, Vokuhl, Christian, Borkhardt, Arndt, Kuhlen, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839031/
https://ncbi.nlm.nih.gov/pubmed/29230040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-017-0048-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados