Loss of Blm enhances basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Ptch1(+/−) mice

Basal cell carcinomas (BCCs) have relative genomic stability and relatively benign clinical behavior but whether these two are related causally is unknown. To investigate the effects of introducing genomic instability into murine BCCs, we have compared ionizing radiation-induced tumorigenesis in Ptc...

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Bibliografiske detaljer
Main Authors: Davari, Parastoo, Hebert, Jennifer L., Albertson, Donna G., Huey, Bing, Roy, Ritu, Mancianti, Maria L., Horvai, Andrew E., McDaniel, Lisa D., Schultz, Roger A., Epstein, Ervin H.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Cancer Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878356/
https://ncbi.nlm.nih.gov/pubmed/19995795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp309
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