Loss of Blm enhances basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Ptch1(+/−) mice

Basal cell carcinomas (BCCs) have relative genomic stability and relatively benign clinical behavior but whether these two are related causally is unknown. To investigate the effects of introducing genomic instability into murine BCCs, we have compared ionizing radiation-induced tumorigenesis in Ptc...

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Detalhes bibliográficos
Main Authors: Davari, Parastoo, Hebert, Jennifer L., Albertson, Donna G., Huey, Bing, Roy, Ritu, Mancianti, Maria L., Horvai, Andrew E., McDaniel, Lisa D., Schultz, Roger A., Epstein, Ervin H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878356/
https://ncbi.nlm.nih.gov/pubmed/19995795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp309
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