Loss of Blm enhances basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Ptch1(+/−) mice

Basal cell carcinomas (BCCs) have relative genomic stability and relatively benign clinical behavior but whether these two are related causally is unknown. To investigate the effects of introducing genomic instability into murine BCCs, we have compared ionizing radiation-induced tumorigenesis in Ptc...

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Bibliographic Details
Main Authors: Davari, Parastoo, Hebert, Jennifer L., Albertson, Donna G., Huey, Bing, Roy, Ritu, Mancianti, Maria L., Horvai, Andrew E., McDaniel, Lisa D., Schultz, Roger A., Epstein, Ervin H.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Cancer Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878356/
https://ncbi.nlm.nih.gov/pubmed/19995795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp309
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