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Topical Thymidine Dinucleotide Treatment Reduces Development of Ultraviolet-Induced Basal Cell Carcinoma in Ptch-1(+/−) Mice

Treatment with thymidine dinucleotide (pTT) has well documented DNA-protective effects and reduces development of squamous cell carcinoma in UV-irradiated mice. The preventive effect of pTT on basal cell carcinoma (BCC) was evaluated in UV-irradiated Ptch-1(+/−) mice, a model of the human disease Go...

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Detalhes bibliográficos
Main Authors: Arad, Simin, Zattra, Edoardo, Hebert, Jennifer, Epstein, Ervin H., Goukassian, David A., Gilchrest, Barbara A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329834/
https://ncbi.nlm.nih.gov/pubmed/18403589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071117
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