Topical DNA oligonucleotide therapy reduces UV-induced mutations and photocarcinogenesis in hairless mice

UV-induced DNA damage gives rise to mutations and skin cancer. We have previously reported that treatment of skin cells in vitro with thymidine dinucleotide (pTT) activates p53 and increases the ability of cells to repair subsequent UV-induced DNA damage by enhancing endogenous DNA repair capacity....

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Goukassian, David A., Helms, Elizabeth, van Steeg, Harry, van Oostrom, Conny, Bhawan, Jag, Gilchrest, Barbara A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC374347/
https://ncbi.nlm.nih.gov/pubmed/14999099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306389101
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares