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Topical DNA oligonucleotide therapy reduces UV-induced mutations and photocarcinogenesis in hairless mice
UV-induced DNA damage gives rise to mutations and skin cancer. We have previously reported that treatment of skin cells in vitro with thymidine dinucleotide (pTT) activates p53 and increases the ability of cells to repair subsequent UV-induced DNA damage by enhancing endogenous DNA repair capacity....
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC374347/ https://ncbi.nlm.nih.gov/pubmed/14999099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306389101 |
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