Increased Sensitivity to UV Radiation in Mice with a p53 Point Mutation at Ser389

Phosphorylation is important for p53 protein stabilization and activation after DNA damage. Serine 389 of p53 is specifically phosphorylated after UV irradiation, whereas gamma radiation activates p53 through a different pathway. To study the in vivo significance of p53 phosphorylation at serine 389...

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主要な著者: Bruins, Wendy, Zwart, Edwin, Attardi, Laura D., Iwakuma, Tomoo, Hoogervorst, Esther M., Beems, Rudolf B., Miranda, Barbara, van Oostrom, Conny T. M., van den Berg, Jolanda, van den Aardweg, Gerard J., Lozano, Guillermina, van Steeg, Harry, Jacks, Tyler, de Vries, Annemieke
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
Cell Growth and Development
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC517897/
https://ncbi.nlm.nih.gov/pubmed/15456863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.20.8884-8894.2004
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