Increased Sensitivity to UV Radiation in Mice with a p53 Point Mutation at Ser389

Phosphorylation is important for p53 protein stabilization and activation after DNA damage. Serine 389 of p53 is specifically phosphorylated after UV irradiation, whereas gamma radiation activates p53 through a different pathway. To study the in vivo significance of p53 phosphorylation at serine 389...

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Bibliografiske detaljer
Main Authors: Bruins, Wendy, Zwart, Edwin, Attardi, Laura D., Iwakuma, Tomoo, Hoogervorst, Esther M., Beems, Rudolf B., Miranda, Barbara, van Oostrom, Conny T. M., van den Berg, Jolanda, van den Aardweg, Gerard J., Lozano, Guillermina, van Steeg, Harry, Jacks, Tyler, de Vries, Annemieke
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC517897/
https://ncbi.nlm.nih.gov/pubmed/15456863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.20.8884-8894.2004
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