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Nuclear cyclin D1: An oncogenic driver in human cancer

Perturbations in the regulation of the core cell cycle machinery are frequently observed in human cancers. Cyclin D1 which functions as a mitogenic sensor and allosteric activator of CDK4/6, is one of the more frequently altered cell cycle regulators in cancers. Cyclin D1 is frequently overexpressed...

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Dades bibliogràfiques
Autors principals: Kim, Jong Kyong, Diehl, J. Alan
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874239/
https://ncbi.nlm.nih.gov/pubmed/19415697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21791
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