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Expression of Constitutively Nuclear Cyclin D1 in Murine Lymphocytes Induces B-Cell Lymphoma
Mantle cell lymphoma (MCL) is a B-cell lymphoma characterized by overexpression of cyclin D1 due to the t(11;14) chromosomal translocation. While expression of cyclin D1 is correlates with MCL development, expression of wild type cyclin D1 transgene in murine lymphocytes is unable to drive B-cell ly...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832762/ https://ncbi.nlm.nih.gov/pubmed/16247460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209147 |
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