載入...
ATM deficiency augments constitutively nuclear cyclin D1-driven genomic instability and lymphomagenesis
Cyclin D1 deregulation is implicated in the genesis of multiple human cancers. Importantly, nuclear cyclin D1 retention during S-phase promotes DNA re-replication and subsequent genomic instability, providing a direct correlation between aberrant cyclin D1/CDK4 activity, transcriptional regulation a...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4112739/ https://ncbi.nlm.nih.gov/pubmed/23318439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.577 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|