Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice

Caspase-2, the most evolutionarily conserved member of the caspase family, has been shown to be involved in apoptosis induced by various stimuli. Our recent work indicates that caspase-2 has putative functions in tumor suppression and protection against cellular stress. As such, the loss of caspase-...

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Bibliografiske detaljer
Main Authors: Puccini, Joseph, Shalini, Sonia, Voss, Anne K., Gatei, Magtouf, Wilson, Claire H., Hiwase, Devendra K., Lavin, Martin F., Dorstyn, Loretta, Kumar, Sharad
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856814/
https://ncbi.nlm.nih.gov/pubmed/24248351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311947110
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