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Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability
Caspase-2 is an initiator caspase, which has been implicated to function in apoptotic and non-apoptotic signalling pathways, including cell-cycle regulation, DNA-damage signalling and tumour suppression. We previously demonstrated that caspase-2 deficiency enhances E1A/Ras oncogene-induced cell tran...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392630/ https://ncbi.nlm.nih.gov/pubmed/22498700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.36 |
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